I filed FB19631435 about this just now. Basically: starting with 15.6, we've had reports (internally and outternally) that after some period of time, networking fails so badly that it can't even acquire a DHCP lease, and the system needs to be rebooted to fix this. The systems in question all have at least 2 VPN applications installed; ours is a transparent proxy provider, and the affected system also had Crowdstrike's Falcon installed. A customer system reported seemingly identical failures on their systems; they don't have Crowdstrike, but they do have Cyberhaven's.
Has anyone else seen somethng like this? Since it seems to involve three different networking extensions, I'm assuming it's due to an interaction between them, not a bug in any individual one. But what do I know? 😄