This has been happening to me for several months, both on Catalina and now on Monterey (I'm on macOS 12.2 with Xcode 13.2.1). And for me, it happens almost 100% of the time. Back in November, I wiped and reinstalled macOS entirely, which seemed to fix my problem for about a month and a half before it started happening again in mid-January. Now it happens to me every time I launch the iPhone simulator.
The only way I've been able to work around this is to delete all my simulators from the organizer in Xcode and re-add them one by one, but I'm now at the point where I have delete and re-add the simulator any time I want to cold boot it. I cleaned my simulators out this morning and cold-booting my one iPhone 12 Pro simulator locked up my computer again this afternoon.
I'll try to gather a sysdiagnose report but given how badly locked up everything is (mouse movement seems okay but that's all that's responsive), I have my doubts I'd be able to get one.
Topic:
Developer Tools & Services
SubTopic:
Xcode
Tags: