Is there a way in App Store Connect to limit Auto Renewable subscriptions to only US

>Is there a way in iTunes Connect

If you mean App Store Connect, regional controi/restriction is at the app level only. Pricing, however, can be territory-centric. From the docs:

Pricing Subscriptions for Each Territory

Auto-renewable subscriptions can offer up to 200 price points across all currencies. You can set the prices you think are suitable for subscribers in different markets, and you have the flexibility to price your subscriptions at parity if they’re available elsewhere.

Pricing Tool. The App Store Connect pricing tool can help you manage pricing based on current exchange rates. If there is a tax change or currency adjustment in a particular region, the price of subscriptions will generally not be affected unless you decide to pass the change on to your users. If you want to change the price of a subscription in a specific market, it’s important to understand which markets are tax inclusive before you take action. For example, if you decide to lower the subscription price for users in Germany, the revenue you’ll receive will be the purchase price minus the European Union’s value added tax (VAT) and minus Apple’s commission. The default pricing in the App Store Connect pricing tool is inclusive of applicable taxes that Apple collects and remits. For more information, review Schedule 2 of the Apple Developer Program License Agreement, which describes territories that have different tax treatments.

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And while you might be able to get creative using location services in the app itself, I'm not sure you'd be able to guarantee you'd let in all you want to let in, and keep everyone out you want to keep out in a scheme-compatible manner. Perhaps if you detailed why you need US-only for an auto renewable someone can offer an actionable solution.