upgrade the macOs to Monterey 12.0.1(21A559) from Mojava, when i login in acoount to Destop, the trackpad not working, so i reset the PRAM/NVRAM and SMC, it don't work as well. i create a new root account and login in, the trackpad work well, but when i restart the system , the trackpad still not working.
Faced the same issue. Trackpad works while system boots up but becomes unusable immediately after logging into the system. For some weird reason this helped:
"System Preferences" -> "Accessibility" -> "Pointer Control" -> uncheck "Ignore built-in trackpad when mouse or wireless trackpad is present".
Never would expect this to work because I have not used any of those external devices with my MBP. What is more surprising is that it continues working even when you turn this option back again.