We are using the CryptoTokenKit framework, specifically the classes TKSmartCardSlotManager, TKSmartCardSlot, and TKSmartCard, to communicate with smart cards through external USB readers on iOS and iPadOS. In most cases, we are able to detect readers via TKSmartCardSlotManager, and send APDU commands using transmitRequest method, with the following code (where self->_slot and self->_card are previously created TkSmartCardSlot and TkSmartCard, respectively): #import - (NSData *)sendCardCommand:(NSData *)command { if (!self->_card || !self->_card.valid || self->_slot.state != TKSmartCardSlotStateValidCard) return nil; NSMutableData *res = [[NSMutableData alloc] init]; NSError *sessionError = nil; [self->_card inSessionWithError:&sessionError executeBlock:^BOOL(NSError **error) { dispatch_semaphore_t semaphore = dispatch_semaphore_create(0); try { [self->_card transmitRequest:command reply:^(NSData * _Nullable response, NSError* _Nullable apduError) { if (apduError != nil) self